PNC-27
PNC-27 is a synthetic fusion peptide containing the MDM2-binding domain of p53 (residues 12–26) linked to a transmembrane-penetrating leader sequence, designed to study p53-MDM2 protein-protein interaction dynamics in cell membrane models. Supplied as a lyophilized powder in a 3mL vial, it is intended exclusively for in vitro laboratory research by qualified scientific personnel.
This peptide has been utilized in preclinical studies examining p53-MDM2 protein binding dynamics, transmembrane signaling mechanisms, apoptotic pathway activity in isolated cell models, and tumor suppressor protein interaction research — independent of the broader cellular effects associated with endogenous p53 pathway activity.
Product Details
- Form: Lyophilized powder (for laboratory research)
- Amount: 5mg or 10mg per vial
- Purity: ≥ 98% (HPLC tested)
- Sequence: (MDM-2 binding domain of p53 fused with penetratin peptide, 27 amino acids)
- Molecular Formula: C₁₄₉H₂₄₄N₄₂O₄₂
- Molecular Weight: ~3281 g/mol
- Intended Use: Laboratory research only
DISCLAIMER: This product is strictly to be used for scientific research use only. It is not for human consumption and the FDA has not approved the use for diagnostic, therapeutic, or medical purposes.
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